테트라하이드로푸란
|
|
테트라하이드로푸란 속성
- 녹는점
- -108°C
- 끓는 점
- 66 °C
- 밀도
- 0.887 g/mL at 20 °C
- 증기 밀도
- 2.5 (vs air)
- 증기압
- <0.01 mm Hg ( 25 °C)
- 굴절률
- n
20/D 1.465
- 인화점
- >230 °F
- 저장 조건
- Store at +5°C to +30°C.
- 용해도
- water: soluble
- 물리적 상태
- Liquid
- Specific Gravity
- 0.89
- 색상
- <10(APHA)
- 상대극성
- 0.207
- 수소이온지수(pH)
- 7-8 (200g/l, H2O, 20℃)
- 냄새
- Ethereal, detectable at 2 to 50 ppm
- pH 범위
- 7
- 폭발한계
- 1.5-12.4%(V)
- 수용성
- miscible
- 어는점
- -108℃
- 감도
- Air Sensitive & Hygroscopic
- 최대 파장(λmax)
- λ: 245 nm Amax: ≤0.26
λ: 275 nm Amax: ≤0.046
λ: 315 μm Amax: ≤0.0044
- Merck
- 14,9211
- BRN
- 102391
- Henry's Law Constant
- 1.54 (static headspace-GC, Welke et al., 1998)
- 노출 한도
- TLV-TWA 200 ppm (590 mg/m3) (ACGIH, MSHA, and OSHA); STEL 250 ppm (ACGIH); IDLH 20,000 ppm (NIOSH).
- 안정성
- Stable. Incompatible with halogens, strong oxidizing agents, strong reducing agents, strong bases, oxygen. May generate explosive peroxides in storage if in contact with air. Highly flammable. Store at room temperature under nitrogen. Hazardous polymerisation may occur. Light sensitive. May contain 2,6-di-tertbutyl-4-methylphenol (BHT) as a s
- InChIKey
- WYURNTSHIVDZCO-UHFFFAOYSA-N
- LogP
- 0.45 at 25℃
- CAS 데이터베이스
- 109-99-9(CAS DataBase Reference)
- IARC
- 2B (Vol. 119) 2019
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,F,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-36/37-19-11-40 | ||
| 안전지침서 | 26-36-33-29-16-46-37-13 | ||
| 유엔번호(UN No.) | UN 2924 3/PG 2 | ||
| WGK 독일 | 1 | ||
| RTECS 번호 | MD0916000 | ||
| F 고인화성물질 | 3-10-23 | ||
| 자연 발화 온도 | 610 °F | ||
| TSCA | Yes | ||
| 위험 등급 | 3 | ||
| 포장분류 | II | ||
| HS 번호 | 29321100 | ||
| 유해 물질 데이터 | 109-99-9(Hazardous Substances Data) | ||
| 독성 | LD50 oral (rat) 2880 mg/kg LC50 inhal (rat) 21,000 ppm (3 h) PEL (OSHA) 200 ppm (590 mg/m3) TLV-TWA (ACGIH) 200 ppm (590 mg/m3) STEL (ACGIH) 250 ppm (737 mg/m3) |
||
| IDLA | 2,000 ppm [10% LEL] | ||
| 기존화학 물질 | KE-33454 |
테트라하이드로푸란 C화학적 특성, 용도, 생산
화학적 성질
Tetrahydrofuran (THF) is an industrial solvent widely recognized for its unique combination of useful properties. DuPont THF is better than 99.9% pure with a small (0.025-0.040 wt % ) amount of butylated hydroxytoluene (BHT, 4-methyl-2,6-di-tertbutyl phenol) added as an antioxidant. Tetrahydrofuran is a cycloaliphatic ether and is not "photochemically reactive" as defined in Section k of Los Angeles County's Rule 66 (equivalent to Rule 442 of the Southern California Air Pollution Control District). THF has an ethereal odor. The Odor Threshold is listed @ 3.8 (3M), 20-50ppm, and 31ppm. It is also a common laboratory reagent and an intermediate in chemical syntheses of consumer and industrial products such as nutritionals, pharmaceuticals, and insecticides (HSDB, 2011).용도
Tetrahydrofuran is used primarily (80%) to make polytetramethylene ether glycol, the base polymer used primarily in the manufacture of elastomeric fibers (e.g., spandex) as well as polyurethane and polyester elastomers (e.g., artificial leather, skateboard wheels). The remainder (20%) is used in solvent applications (e.g., pipe cements, adhesives, printing inks, and magnetic tape) and as a reaction solvent in chemical and pharmaceutical syntheses.반응 프로필
Tetrahydrofuran reacts violently with oxidizing agents leading to fires and explosions [Handling Chemicals Safely 1980. p. 891]. Subject to peroxidation in the air. Peroxides or their products react exothermically with lithium aluminum hydride [MCA Guide for Safety 1973]. Thus, use as a solvent for lithium aluminum hydride has led to fires. Using potassium hydroxide or sodium hydroxide to dry impure Tetrahydrofuran that contains peroxides has resulted in explosions. A violent explosion occurred during the preparation of sodium aluminum hydride from sodium and aluminum in a medium of Tetrahydrofuran [Chem. Eng. News 39(40):57. 1961]. THF forms explosive products with 2-aminophenol [Lewis 3227].인화성 및 폭발성
THF is extremely flammable (NFPA rating = 3), and its vapor can travel a considerable distance to an ignition source and "flash back." A 5% solution of THF in water is flammable. THF vapor forms explosive mixtures with air at concentrations of 2 to 12% (by volume). Carbon dioxide or dry chemical extinguishers should be used for THF fires.THF can form shock- and heat-sensitive peroxides, which may explode on concentration by distillation or evaporation. Always test samples of THF for the presence of peroxides before distilling or allowing to evaporate. THF should never be distilled to dryness.
잠재적 노출
The primary use of tetrahydrofuran is as a solvent to dissolve synthetic resins, particularly polyvinyl chloride and vinylidene chloride copolymers. It is also used to cast polyvinyl chloride films, to coat substrates with vinyl and vinylidene chloride; and to solubilize adhesives based on or containing polyvinyl chloride resins. A second large market for THF is as an electrolytic solvent in the Grignard reaction-based production of tetramethyl lead. THF is used as an intermediate in the production of polytetramethylene glycol.Carcinogenicity
THF showed little evidence of mutagenic activity in a variety of in vitro and in vivo assays.저장
THF should be used only in areas free of ignition sources, and quantities greater than 1 liter should be stored in tightly sealed metal containers in areas separate from oxidizers. Containers of THF should be dated when opened and tested periodically for the presence of peroxides.비 호환성
Forms thermally explosive peroxides in air on standing (in absence of inhibitors). Peroxides can be detonated by heating, friction, or impact. Reacts violently with strong oxidizers, strong bases and some metal halides. Attacks some forms of plastics, rubber and coatings.폐기물 처리
Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Concentrated waste containing peroxides-perforation of a container of the waste from a safe distance followed by open burning.테트라하이드로푸란 준비 용품 및 원자재
원자재
네오프렌
Uraldehyde
1,4-부탄디올
니켈
클로로프렌
IRISH MOSS
PALLADIUM-CATALYSTS
수소
Metallic oxides
cis-1,4-Dichloro-2-butene
뷰티로락톤
준비 용품
Jiuma plate amino-acid surfactant
SODIUM PHENOLATE TRIHYDRATE
노르에티스테론
부틸벤질알콜
1-(2-NAPHTHYL)METHANAMINE
9-안트라센메탄올
Chiral 2，2-Disubstituted thiaprolinol derivatives
(R)-TERT-LEUCINOL
2-(4-tert-부틸페닐)에탄올
1,4-Butane sultone
Erythromycin ethylsuccinate
3-tert-butyl-1H-1,2,4-triazole-5-thiol
N-methylaminoethanol sodium phosphate
4-Amino-5-bromo-2-chloropyrimidine
1,4-Diiodobutane
L(+)-Leucinol
2-Chloroisonicotinaldehyde
세탈코늄클로라이드
(S)-(-)-4-tert-Butyloxazolidine-2,5-dione
7-Fluoroindole
L-Tryptophanol
4-Chlorobutylbenzoate
TERT-BUTYLMAGNESIUM CHLORIDE
(S)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol
BENZO[B]THIOPHENE-2-CARBOXALDEHYDE
2,5-디메틸피페라진
Quinestrol
Allylmagnesium chloride
레보노게스트렐
N-(2-Aminoethyl)piperidine
2,3,4-Tribromothiophene
(4-AMINO-PYRIDIN-3-YL)-METHANOL
3-Cyanophenylboronic acid
Dioctyl(maleate)tin
Cyclopropylacetic acid
2,3-Difluorophenylboronic acid
2,2'-DIPYRIDYLAMINE
Vinylferrocene
테트라히드로티오펜
(1,5-DIMETHYL-1H-PYRAZOL-3-YL)METHANOL
테트라하이드로푸란 공급 업체
글로벌( 1032)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shandong Yanshuo Chemical Co., Ltd. | +86-18678179670 +86-18615116763 |
sales@yanshuochem.com | China | 101 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2990 | 55 |
| Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 |
sales@tjzxchem.com | China | 548 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1005@dideu.com | China | 9812 | 58 |
| Hebei Duling International Trade Co. LTD | +86-0311-87836622; +8613126117136 |
sales06@hbduling.cn | China | 15815 | 58 |
| Zouping mingyuan import & export trading co., ltd | +86-0543-2240078 +8618364991597 |
myzhao793@163.com | China | 994 | 58 |
| Shijiazhuang Suking Biotechnology Co .,Ltd. | +86-17318586295 |
sales1@sxbiology.com | China | 291 | 58 |
| Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 |
admin@china-yime.com | China | 764 | 58 |
| Hebei Ruiyao Biotechnology Co. Ltd | +86-19932785305 +86-19932785305 |
Zoey06@aliyun.com | China | 311 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29811 | 60 |