2,6-루티딘
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2,6-루티딘 속성
- 녹는점
- -6 °C (lit.)
- 끓는 점
- 143-145 °C (lit.)
- 밀도
- 0.92 g/mL at 25 °C (lit.)
- 증기압
- 5.5 hPa (20 °C)
- 굴절률
- n
20/D 1.497(lit.)
- 인화점
- 92 °F
- 저장 조건
- −20°C
- 용해도
- Chloroform (Soluble), Methanol (Slightly)
- 산도 계수 (pKa)
- 6.65(at 25℃)
- 물리적 상태
- Liquid
- 색상
- Clear
- 냄새
- at 1.00 % in dipropylene glycol. nutty amine woody bready cocoa oily
- ?? ??
- nutty
- 수용성
- 40 g/100 mL (20 ºC)
- 감도
- Hygroscopic
- JECFA Number
- 1317
- Merck
- 14,5616
- BRN
- 105690
- 안정성
- Stable. Flammable. Incompatible with strong oxidizing agents, acid chlorides, acids, chloroformates. Protect from moisture.
- LogP
- 0.12 at 25℃
- CAS 데이터베이스
- 108-48-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,F,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 10-22-36/37/38-20/21/22 | ||
안전지침서 | 26-36/37-16-36-36/37/39 | ||
유엔번호(UN No.) | UN 1993 3/PG 3 | ||
WGK 독일 | 3 | ||
RTECS 번호 | OK9700000 | ||
F 고인화성물질 | 8 | ||
위험 참고 사항 | Irritant/Flammable | ||
TSCA | Yes | ||
위험 등급 | 3 | ||
포장분류 | III | ||
HS 번호 | 29333999 | ||
유해 물질 데이터 | 108-48-5(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: 400 mg/kg LD50 dermal Rabbit > 1000 mg/kg | ||
기존화학 물질 | KE-11843 |
2,6-루티딘 C화학적 특성, 용도, 생산
화학적 성질
Colorless to yellow liquid출처
Reported found in bread, tea, peppermint oil, cheeses, chicken, beef, pork, beer, sherry, whiskies, cocoa, coffee, tea, oatmeal, rice bran, buckwheat and malt.용도
2,6-Lutidine is used as a solvent in organic synthesis and as a sterically hindered mild base. It is also used as a vulcanization accelerator for dyes, resins and rubber. It also acts as a food additive.정의
ChEBI: A member of the class of methylpyridines that is pyridine carrying methyl substituents at positions 2 and 6.일반 설명
A colorless liquid with a peppermint odor. Flash point 92°F. Less dense than water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Used to make other chemicals.공기와 물의 반응
Highly flammable. Soluble in water.반응 프로필
2,6-Lutidine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.건강위험
Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.Purification Methods
Likely contaminants include 3-and 4-picoline (similar boiling points). However, they are removed by using BF3, with which they react preferentially, by adding 4mL of BF3 to 100mL of dry fractionally distilled 2,6-lutidine and redistilling. Distillation of commercial material from AlCl3 (14g per 100mL) can also be used to remove picolines (and water). Alternatively, lutidine (100mL) can be refluxed with ethyl benzenesulfonate (20g) or ethyl p-toluenesulfonate (20g) for 1hour, then the upper layer is cooled, separated and distilled. The distillate is refluxed with BaO or CaH2, then fractionally distilled through a glass helices-packed column. 2,6-Lutidine can be dried with KOH or sodium or by refluxing with (and distilling from) BaO, prior to distillation. For purification via its picrate, 2,6-lutidine, dissolved in absolute EtOH, is treated with an excess of warm ethanolic picric acid. The precipitate is filtered off, recrystallised from acetone (to give m 163-164.5o (166-167o), and partitioned between ammonia and CHCl3/diethyl ether. The organic layer, after washing with dilute aqueous KOH, is dried with Na2SO4 and fractionally distilled. [Warnhoff J Org Chem 27 4587 1962.] Alternatively, 2,6-lutidine can be purified via its urea complex, as described under 2,3-lutidine. Other purification procedures include azeotropic distillation with phenol [Coulson et al. J Appl Chem (London) 2 71 1952], fractional crystallisation by partial freezing, and vapour-phase chromatography using a 180-cm column of polyethylene glycol-400 (Shell, 5%) on Embacel (May and Baker) at 100o, with argon as carrier gas [Bamford & Block J Chem Soc 4989 1961]. The hydrochloride has m 235-237o, 239o (from EtOH). [Beilstein 20 II 160, 20 III/IV 2776, 20/6 V 32.]2,6-루티딘 준비 용품 및 원자재
원자재
준비 용품
2-(HYDROXYETHYL)-6-METHYLPYRIDINE
2,6-BIS(CHLOROMETHYL)PYRIDINE
다이피콜린산
3-Bromo-2,6-dimethylpyridine
7-BROMO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE
2,4-루티딘
2,6-Dimethyl-3-nitropyridine
5-bromo-1,2,3,4-tetrahydroisoquinoline
Cefpiramide acid
2,6-피리딘디메탄올
6-BROMOMETHYL-2-PYRIDINECARBOXYLIC ACID
5-메톡시소라렌
2-(Bromomethyl)-6-methylpyridine
2,6-DIMETHYL-PYRIDIN-4-YLAMINE
2,6-Dimethylpyridine N-oxide
6-Methyl-2-pyridinecarboxylic acid
3-AMINO-2,6-DIMETHYLPYRIDINE
2-METHYL-6-VINYLPYRIDINE
(2S,6S)-2,6-dimethylpiperidine
2,6-루티딘 공급 업체
글로벌( 510)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | 15028179902 +8615028179902 |
sales@hbmojin.com | China | 7044 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29811 | 60 |
Henan DaKen Chemical CO.,LTD. | +86-371-66670886 |
info@dakenchem.com | China | 18729 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21975 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 31969 | 60 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29922 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | CHINA | 2933 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28184 | 58 |