L-(+)-발린
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L-(+)-발린 속성
- 녹는점
- 295-300 °C (subl.) (lit.)
- 알파
- 28 º (c=8, 6N HCl)
- 끓는 점
- 213.6±23.0 °C(Predicted)
- 밀도
- 1.23
- 굴절률
- 28 ° (C=8, HCl)
- 저장 조건
- 2-8°C
- 용해도
- H2O: 25 mg/mL
- 물리적 상태
- powder
- 산도 계수 (pKa)
- 2.29(at 25℃)
- 색상
- White
- 수소이온지수(pH)
- 5.5-6.5 (100g/l, H2O, 20℃)
- 냄새
- odorless
- ?? ??
- odorless
- optical activity
- [α]20/D +27.0±0.5°, c = 5% in 5 M HCl
- 수용성
- 85 g/L (20 ºC)
- 최대 파장(λmax)
- λ: 260 nm Amax: 0.15
λ: 280 nm Amax: 0.1
- Merck
- 14,9909
- BRN
- 1721136
- InChIKey
- KZSNJWFQEVHDMF-BYPYZUCNSA-N
- LogP
- 0.29
- CAS 데이터베이스
- 72-18-4(CAS DataBase Reference)
- NIST
- Valine(72-18-4)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 40 | ||
| 안전지침서 | 24/25-36-22 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | YV9361000 | ||
| TSCA | Yes | ||
| HS 번호 | 29224995 | ||
| 유해 물질 데이터 | 72-18-4(Hazardous Substances Data) | ||
| 독성 | LD50 intraperitoneal in rat: 5390mg/kg | ||
| 기존화학 물질 | KE-01453 |
L-(+)-발린 C화학적 특성, 용도, 생산
개요
Valine (abbreviated as Val or V) is an α-amino acid with the chemical formula HO2CCH(NH2)CH(CH3)2. L-Valine is one of 20 proteinogenic amino acids. Its codons are GUU, GUC, GUA, and GUG. This essential amino acid is classified as nonpolar. Human dietary sources are any proteinaceous foods such as meats, dairy products, soy products, beans and legumes.Along with leucine and isoleucine, valine is a branched-chain amino acid. It is named after the plant valerian. In sickle-cell disease, valine substitutes for the hydrophilic amino acid glutamic acid in hemoglobin. Because valine is hydrophobic, the hemoglobin is prone to abnormal aggregation.
화학적 성질
White or almost white, crystalline powder or colourless crystals, soluble in water, very slightly soluble in alcohol.용도
L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grai ns, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.정의
ChEBI: The L-enantiomer of valine.Biosynthesis
Valine is an essential amino acid, hence it must be ingested, usually as a component of proteins. It is synthesized in plants via several steps starting from pyruvic acid. The initial part of the pathway also leads to leucine. The intermediate α-ketoisovalerate undergoes reductive amination with glutamate. Enzymes involved in this biosynthesis include :Acetolactate synthase
Acetohydroxy acid isomeroreductase
Dihydroxyacid dehydratase
Valine aminotransferase.
일반 설명
Valine is an essential amino acid, involved in the biosynthesis of glutamine and alanine. Valine being a branched-chain amino acid (BCAA), maintains a balance among the BCAAs. L-Valine serves as an energy fuel.Safety Profile
Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.Purification Methods
Crystallise L-valine from water by addition of EtOH. It sublimes at 178-188o/0.03mm with 99.3% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Perrin J Chm Soc 3125 1958, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2368-23771961, Beilstein 4 IV 2659.]L-(+)-발린 준비 용품 및 원자재
원자재
DL- amino acids
말토덱스트린
히단토인
이소부탄올
L-글루타민산
Valine
DL-Valine
요소
시안화수소
이소부틸알데히드
암모늄 카보네이트
부소부틸로니트릴
L-(-)-세린
L-(+)-아이소루신
준비 용품
L-(+)-발린 공급 업체
글로벌( 893)공급 업체
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