바요주석

바요주석
바요주석 구조식 이미지
카스 번호:
58-85-5
한글명:
바요주석
동의어(한글):
바이오틴;비오틴;바요주석;바이오주석;비타민H
상품명:
D-Biotin
동의어(영문):
BIOTIN;VITAMIN B7;VITAMIN H;5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanoic acid;BIOEPIDERM;5-(2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid;BIOS H;BIOTINUM;BIOTIN(V-H);ETHYLPHENYLETHANOL
CBNumber:
CB3271542
분자식:
C10H16N2O3S
포뮬러 무게:
244.31
MOL 파일:
58-85-5.mol

바요주석 속성

녹는점
231-233 °C(lit.)
알파
89 º (c=1, 0.1N NaOH)
끓는 점
573.6±35.0 °C(Predicted)
밀도
1.2693 (rough estimate)
굴절률
90.5 ° (C=2, 0.1mol/L NaOH)
저장 조건
-20°C
용해도
H2O: 0.2 mg/mL Solubility increases with addition of 1 N NaOH.
물리적 상태
powder
산도 계수 (pKa)
4.74±0.10(Predicted)
색상
White crystalline powder or fine long needles
수소이온지수(pH)
4.5 (0.1g/l, H2O)
optical activity
[α]20/D +91±2°, c = 1% in 0.1 M NaOH
수용성
Soluble in hot water, dimethyl sulfoxide, alcohol and benzene.
감도
Light Sensitive
Merck
14,1231
BRN
86838
안정성
Stable, but light sensitive. Incompatible with strong oxidizing agents, strong bases, strong acids, formaldehyde, chloramine-T, nitrous acid.
InChIKey
YBJHBAHKTGYVGT-ZKWXMUAHSA-N
LogP
0.861 (est)
CAS 데이터베이스
58-85-5(CAS DataBase Reference)
NIST
Biotin(58-85-5)
EPA
Biotin (58-85-5)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 20/21/22-36/37/38
안전지침서 24/25-36-26
WGK 독일 1
RTECS 번호 XJ9088200
F 고인화성물질 8
TSCA Yes
HS 번호 29362930
유해 물질 데이터 58-85-5(Hazardous Substances Data)
독성 LD50 orally in Rabbit: > 2000 mg/kg
기존화학 물질 KE-18590
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
NFPA 704
0
1 0

바요주석 MSDS


Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid

바요주석 C화학적 특성, 용도, 생산

화학적 성질

White powder

용도

Growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue.

정의

ChEBI: An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins.

일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Biotin is a water-soluble vitamin, essential for amino acids and carbohydrates metabolism. It is involved in de novo synthesis of purine nucleotides and plays a role in gene expression and DNA replication.

Safety Profile

An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.

Purification Methods

D-(+)-Biotin crystallises from hot water in fine long needles with a solubility of 22 mg/100mL at 25o. Its solubility in 95% EtOH is 80 mg/100 mL at 25o. Its isoelectric point is at pH 3.5. Store solid and solutions under sterile conditions because it is susceptible to mould growth. [Confalone J Am Chem Soc 97 5936 1975, Wolf et al. J Am Chem Soc 67 2100 1945, Synthesis: Ohuri & Emoto Tetrahedron Lett 2765 1975, Harris et al. J Am Chem Soc 66 1756 1944.] The (+)-methyl ester has m 166-167o (from MeOH/Et2O), [] D 22 +57o (c 1, CHCl3) [du Vigneaud et al. J Biol Chem 140 643, 763 1941]; the (+)-S-oxide has m 200-203o, [] D 20 +130o (c 1.2, 0.1N NaOH) [Melville J Biol Chem 208 495 1954]; the SS-dioxide has m 274-275o(dec, 268-270o), and the SS-dioxide methyl ester has m 239-241o (from MeOH/Et2O) [Hofmann et al. J Biol Chem 141 207, 213 1941]. [Beilstein 27 III/IV 7979.]

바요주석 준비 용품 및 원자재

원자재

준비 용품


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