L-(-)-페닐알라닌

L-(-)-페닐알라닌
L-(-)-페닐알라닌 구조식 이미지
카스 번호:
63-91-2
한글명:
L-(-)-페닐알라닌
동의어(한글):
(S)-알파-아미노벤젠프로피온산;(S)-페닐알라닌;3-페닐알라닌;L-(-)-페닐알라닌;L-페닐알라닌;베타-페닐알라닌;알라닌,페닐-,L-;알파-아미노히드로신남산;페닐알라닌;페닐-알파-알라닌;페닐알라닌ℓ;(S)- 아미노페닐프로피온 산;L-(-)페닐알라닌;알라닌, 페닐-,L-
상품명:
L-Phenylalanine
동의어(영문):
PHENYLALANINE;PHE;F;L-PHE;H-PHE-OH;Phenylalanin;L-Phenylalanin;H-L-PHE-OH;3-Phenylalanine;PHENYALANINE, L-
CBNumber:
CB2488691
분자식:
C9H11NO2
포뮬러 무게:
165.19
MOL 파일:
63-91-2.mol

L-(-)-페닐알라닌 속성

녹는점
270-275 °C (dec.)(lit.)
알파
-34.1 º (c=2, water, dry basis)
끓는 점
293.03°C (rough estimate)
밀도
1.29
증기압
<1 Pa (25 °C)
FEMA
3585 | L-PHENYLALANINE
굴절률
-34 ° (C=2, H2O)
저장 조건
Store below +30°C.
용해도
H2O: 0.1 M at 20 °C, clear, colorless
물리적 상태
powder
산도 계수 (pKa)
2.2(at 25℃)
색상
White to off-white
수소이온지수(pH)
5.0-7.0 (25℃, 0.1M in H2O)
냄새
at 100.00 %. odorless
?? ??
odorless
optical activity
[α]25/D -34.2°, c = 2 in H2O (dried basis)
수용성
1-5 g/100 mL at 25 ºC
Merck
14,7271
JECFA Number
1428
BRN
1910408
안정성
Stable. Incompatible with strong oxidizing agents.
InChIKey
COLNVLDHVKWLRT-QMMMGPOBSA-N
LogP
0.24
CAS 데이터베이스
63-91-2(CAS DataBase Reference)
NIST
L-Phenylalanine(63-91-2)
EPA
L-Phenylalanine (63-91-2)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 C
위험 카페고리 넘버 36/37/38-34
안전지침서 22-24/25-37/39-45-36/37/39-27-26
WGK 독일 3
RTECS 번호 AY7535000
F 고인화성물질 10
TSCA Yes
HS 번호 29224995
유해 물질 데이터 63-91-2(Hazardous Substances Data)
기존화학 물질 KE-01557
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
1 0

L-(-)-페닐알라닌 MSDS


L-Phenylalanine

L-(-)-페닐알라닌 C화학적 특성, 용도, 생산

화학적 성질

L-Phenylalanine has no odor and a slight bitter taste. It melts with decomposition at about 283°C. The pH of a 1 in 100 solution is between 5.4 and 6.0. FEMA notes this chemical is used in cocoa substitute only.

출처

Reported found in white bread, macaroni, egg noodles, corn flakes, corn grits, oatmeal, wheat bran, wheat flakes, shredded wheat, barley, brown rice, rye flour, whole grain wheat flour, buttermilk, blue cheese, cheddar cheese, cottage cheese, cream cheese, parmesan cheese, bacon, cured ham, frankfurters, pork sausage, canned red kidney beans, canned sweet corn, canned peas, canned lima beans, canned potatoes, canned asparagus, canned snap beans, canned beets, beef, lamb, fresh ham, veal round, beef liver, chicken, chicken liver, turkey and other natural sources.

용도

L-Phenylalanine is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and further conv erted into dopamine, norepinephrine, and epinephrine. L-Phenylalanine is produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.

정의

ChEBI: The L-enantiomer of phenylalanine.

제조 방법

From PTS-negative Escherichia coli bioengineered strains.

일반 설명

Odorless white crystalline powder. Slightly bitter taste. pH (1% aqueous solution) 5.4 to 6.

공기와 물의 반응

Water soluble. Aqueous solutions are weak acids.

반응 프로필

L-Phenylalanine may be light sensitive. Act as weak acids in solution.

건강위험

ACUTE/CHRONIC HAZARDS: When heated to decomposition L-Phenylalanine emits toxic fumes of nitrogen oxides.

화재위험

Flash point data for L-Phenylalanine are not available; however, L-Phenylalanine is probably combustible.

Safety Profile

Mildly toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Likely impurities are leucine, valine, methionine and tyrosine. Crystallise L-phenylalanine from water by adding 4volumes of EtOH. Dry it in vacuo over P2O5. Also crystallise it from saturated refluxing aqueous solutions at neutral pH, or 1:1 (v/v) EtOH/water solution, or conc HCl. It sublimes at 176-184o/0.3mm with 98.7% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2156-2175 1961, Beilstein 14 IV 1552.]

L-(-)-페닐알라닌 준비 용품 및 원자재

원자재

준비 용품


L-(-)-페닐알라닌 공급 업체

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