N-메틸모폴린
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N-메틸모폴린 속성
- 녹는점
- −66 °C(lit.)
- 끓는 점
- 115-116 °C750 mm Hg(lit.)
- 밀도
- 0.92 g/mL at 25 °C(lit.)
- 증기 밀도
- >1 (vs air)
- 증기압
- 18 mm Hg ( 20 °C)
- 굴절률
- n
20/D 1.435(lit.)
- 인화점
- 75 °F
- 저장 조건
- Store below +30°C.
- 용해도
- Chloroform (Soluble), Ethyl Acetate, Methanol (Slightly)
- 물리적 상태
- Liquid
- 산도 계수 (pKa)
- 7.38(at 25℃)
- 색상
- Clear
- Specific Gravity
- 0.920 (20/4℃)
- 수소이온지수(pH)
- 10.6 (50g/l, H2O, 20℃)
- 폭발한계
- 2.1%(V)
- 수용성
- >500 g/L (20 ºC)
- Merck
- 14,6277
- BRN
- 102719
- 안정성
- Volatile
- InChIKey
- SJRJJKPEHAURKC-UHFFFAOYSA-N
- LogP
- -0.32 at 25℃
- CAS 데이터베이스
- 109-02-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | F,C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 11-20/21/22-34-10-22 | ||
| 안전지침서 | 16-26-36/37/39-45-25 | ||
| 유엔번호(UN No.) | UN 2535 3/PG 2 | ||
| WGK 독일 | 1 | ||
| RTECS 번호 | QE5775000 | ||
| F 고인화성물질 | 10-23 | ||
| 자연 발화 온도 | 165 °C DIN 51794 | ||
| TSCA | Yes | ||
| 위험 등급 | 3 | ||
| 포장분류 | II | ||
| HS 번호 | 29349990 | ||
| 독성 | LD50 orally in Rabbit: 1960 mg/kg LD50 dermal Rabbit 1240 mg/kg | ||
| 기존화학 물질 | KE-24448 |
N-메틸모폴린 C화학적 특성, 용도, 생산
화학적 성질
colorless and transparent liquid. with characteristic odor. soluble in organic solvents, miscible with water and ethanol.용도
4-Methylmorpholine is used as a solvent for dyes, resins, waxes and pharmaceuticals. It acts as a crosslinker in the preparation of polyurethane foams, elastomers and adhesives. It is used as a precursor to prepare N-methylmorpholine N-oxide and morpholinium cation based ionic liquids. It is utilized as corrosion inhibitors and anti-scaling agents in industries.제조 방법
4-Methylmorpholine preparation method is to slowly add formaldehyde in morpholine drop by drop, under stirring add formic acid reaction, automatic reflux, and release carbon dioxide. After adding formic acid, heating reflux 4 ~ 5h, cooling and adding sodium hydroxide immediately distillation, collect all the fraction before the boiling point of 99 ℃, and then add sodium hydroxide in the fraction to saturation, cooling the oil layer, drying, fractional distillation, to obtain N-methylmorpholine.일반 설명
A water-white liquid with an ammonia-like odor. Less dense than water and insoluble in water. Flash point 75°F. May be moderately toxic by ingestion, inhalation and skin absorption. Very irritating to skin, eyes, and mucous membranes. Used as a solvent and to make pharmaceuticals.공기와 물의 반응
Highly flammable. Insoluble in water.반응 프로필
Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.위험도
Flammable, dangerous fire risk. Skin irri-tant.건강위험
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.화재위험
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.Safety Profile
Moderately toxic by ingestion and skin contact. Mildly toxic by inhalation. An irritant to skin, eyes, and mucous membranes. Flammable when exposed to heat or flame, can react vigorously with oxidizing materials. When heated to decomposition it emits toxic fumes of NOx.Purification Methods
Dry it by refluxing with BaO or sodium, then fractionally distil it through a helices-packed column. The picrate has m 227o, the thiocyanate salt has m 103o (from butanone). [Hall J Phys Chem 60 63 1956, Beilstein 27 I 203, 27 III/IV 22.]N-메틸모폴린 준비 용품 및 원자재
원자재
다이에틸렌 글리콜
메틸아민
포르말린
개미산
비스(2-클로로에틸) 에테르
모르폴린
글리옥실산
암모니아(가스)
Ethanamine, N,N-dimethyl-2-[2-(methylamino)ethoxy]-
4-포르밀모폴린
4-메틸모르폴린 4-산화물
2-(2-(디메틸아미노)에폭시)에탄올
N-메틸다이에탄올아민
준비 용품
Tenidap
Fosinopril
Cefpiramide acid
Benazepril
4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methyl morpholinium chloride
Azasetron hydrochloride
3-Amino-5-fluoropyridine
1-Boc-4-(aminomethyl)piperidine
3-Aminomethyl-1-N-Boc-piperidine
4-Methylmorpholine N-oxide monohydrate
Zafirlukast
1-Hydroxybenzotriazole hydrate
Alacepril
N-메틸모폴린 공급 업체
글로벌( 513)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 |
sales@senfeida.com | China | 4929 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29811 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21975 | 55 |
| Guangzhou PI PI Biotech Inc | +86-020-81716320 +86-18371201331 |
Sales@pipitech.com | China | 3635 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2990 | 55 |
| Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 |
sales@tjzxchem.com | China | 548 | 58 |
| Yancheng Green Chemicals Co.,Ltd | +undefined-86-25-86655873 |
info@royal-chem.com | China | 106 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29922 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | CHINA | 2933 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28184 | 58 |