Glutathion Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R68:Irreversibler Schaden möglich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getränkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
Glutathione (GSH) is a tripeptide (γ-
glutamylcysteinylglycine) widely distributed in both plants and animals. GSH serves as a nucleophilic co-
substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH is also involved in amino acid transport and maintenance of protein sulfhydryl reduction status. The concentration of GSH ranges from a few micromolar in plasma to several millimolar in tissues such as liver.
Chemische Eigenschaften
White cryst. powder
Definition
ChEBI: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Allgemeine Beschreibung
Glutathione (GSH) is the most important nonprotein thiol widely distributed in animal tissues, plants, and microorganisms. GSH is also a key determinant of redox signaling and protection against oxidative stress.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Sicherheitsprofil
Moderately toxic by
intravenous route. Experimental
reproductive effects. Human mutation data
reported. When heated to decomposition it
emits very toxic fumes of SOx and NOx.
läuterung methode
Crystallise L-glutathione from 50% aqueous EtOH, dry it in a vacuum and
Glutathion Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
