3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-on
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- CAS-Nr.
- 529-44-2
- Bezeichnung:
- 3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-on
- Englisch Name:
- Myricetin
- Synonyma:
- MYRICETOL;bayberry bark extract;MYRICETIN 95%;CANNABISCETIN;3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one;MYRISETIN;MYRICETIN;NSC 407290;LDN 0014058;Myricetin>
- CBNumber:
- CB5142262
- Summenformel:
- C15H10O8
- Molgewicht:
- 318.24
- MOL-Datei:
- 529-44-2.mol
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3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-on Eigenschaften
- Schmelzpunkt:
- >300 °C(lit.)
- Siedepunkt:
- 377.41°C (rough estimate)
- Dichte
- 1.4222 (rough estimate)
- Brechungsindex
- 1.4395 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- ethanol: soluble10mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow
- pka
- 6.30±0.40(Predicted)
- Aggregatzustand
- crystalline
- Farbe
- Yellowish Brown
- Wasserlöslichkeit
- Soluble in dimethyl sulfoxide,dimethyl formamide and ethanol. Insoluble in water.
- Merck
- 14,6332
- BRN
- 332331
- Stabilität:
- Hygroscopic
- InChIKey
- IKMDFBPHZNJCSN-UHFFFAOYSA-N
- LogP
- 1.206 (est)
- CAS Datenbank
- 529-44-2(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-on Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Myricetin is a flavonoid compound found in many fruits and vegetables, including red wine, that acts as a powerful antioxidant. Myricetin inhibits TBARS formation with an IC
50 value of 6.34 and at 20 μM, blocks oxLDL uptake by U937-derived macrophages, reducing CD36 expression. Myricetin demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit the neoplastic transformation of murine JB6 P+ cells and inhibiting MEK1 kinase activity.
Chemische Eigenschaften
brown-yellow to brown-green crystalline powder
Verwenden
Myricetin is used as an antioxidant. It is a cell-permeable flavonoid used in inflammatory, diabetes, and cancer studies. It is effective in protecting neurons against oxidative stresses. Further, it inhibits yeast alfa-glucosidase,1 glyoxalase I in vitro and bovine milk xanthine oxidase.
Definition
ChEBI: A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants.
Allgemeine Beschreibung
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.
läuterung methode
Myricetin (Cannabiscetin, 3,3',4',5,5',7-hexahydroxyflavone) [529-44-2] M 318.2, m > 3 0 0o, 357o(dec) (polyphenolic pKEst~8-11). Recrystallise myricetin from aqueous EtOH (m 357o dec, as monohydrate) or Me2CO (m 350o dec, with one mol of Me2CO) as yellow crystals. It is almost insoluble in CHCl3 and AcOH. The hexaacetate has m 213o. [Hergert J Org Chem 21 534 1956, Spada & Cameroni Gazzetta 86 965, 975 1956, Kalff & Robinson J Chem Soc 127 181 1925, Beilstein 18/5 V 670.]
3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one
3-[(6-Desoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-benzopyran-4-on
5,7-DIHYDROXY-3,3',4',5'-TETRAMETHOXYFLAVONE
Dihydromyricetin
Downstream Produkte
3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 397)Lieferanten
529-44-2(3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-on)Verwandte Suche:
- 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)
- CANNABISCETIN(SEE MYRICETIN)(P)
- MYRICETIN(CANNABISCETIN)(P)
- MYRICETIN(CANNABISCETIN)(RG)
- MYRISETIN
- 3,3,4,4,5,7-hexahydro-2-phenyl-4H-chromen-4-one
- MYRICETIN 95%
- Myricetin, froM Myrica rubra (Lour.) Zucc.
- 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one
- CANNABISCETIN hplc
- CANNABISCETIN
- 3,3',4',5,5',7-HEXAHYDROXYFLAVONE
- 3',4',5',3,5,7-HEXAHYDROXYFLAVONE
- 3,5,7,3',4',5'-HEXAHYDROXYFLAVONE
- MYRICETIN
- MYRICETOL
- Myricetin
3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one
- Myricetin - CAS 529-44-2 - Calbiochem
- Myricetin, 98%, from Myrica rubra (Lour.) Zucc.
- Myricetin Cannabiscetin 529-44-2
- bayberry bark extract
- MYRICETIN >= 96.0% (HPLC)
- Baberry Bark Extract
- MYRICETIN WITH HPLC
- (3,4,5-trihydroxyphenyl)-
- 4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-
- 3,3μ,4μ,5,5μ,7-Hexahydroxyflavone, Cannabiscetin
- 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
- Myricetin,95%
- Myricetin3,3',4',5,5',7-Hexahydroxyflavone
- 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
- Myricetin,3,3′,4′,5,5′,7-Hexahydroxyflavone, Cannabiscetin
- MYRICETIN(CANNABISCETIN)(SH)
- Myricetin(Cannabiscetin)
- 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-
- LDN 0014058
- NSC 407290
- 3,3’,4’,5,5’,7-hexahydroxy-flavon
- 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on
- Myricetin, 95% 25MG
- Myricetin 80%-98%
- Myricetin>
- Cortex Myricae extract Myricetin
- MyricetinQ: What is
Myricetin Q: What is the CAS Number of
Myricetin Q: What is the storage condition of
Myricetin Q: What are the applications of
Myricetin
- Myricetin, ≥96%
- 2-Methyl-1-butanol 137-32-6
- 529-44-2
- C15H10O8
- Serine/Threonine Kinase Inhibitors
- Protein Kinase C, Mitogen-activated protein kinase, c-Jun N-terminal Kinase (PKC, MAPK and Jnk)
- Kinase/Phosphatase Biology
- BioChemical
- Cell Signaling and Neuroscience
- Cell Biology
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
